Completely on her own, Sarah spends her time at home, waiting for the approaching birth of her child. But one night, a stranger breaks into her home, ready to snatch her still unborn baby from her.
After the strange death of his young son at their new home, Daniel hears a ghostly plea for help, spurring him to seek out a renowned paranormal expert.
Apartment concierge Cesar (Luis Tosar) is a miserable person who believes he was born without the ability to be happy. As a result, he decides his mission is to make life hell for everyone around him. A majority of the tenants are easy to agitate, but Clara (Marta Etura) proves to be harder than the most. So Cesar goes to creepy extremes to make this young woman mentally break down. Things get even more complicated in this twisted relationship when her boyfriend, Marcos (Alberto San Juan), shows up.
Suddenly, Clara, Mónica's daughter, falls into a deep coma. With Clara left to die, a mysterious man proposes Monica to make a pact: Clara will be saved if Mónica does something for him.
Lucía and her son live isolated from society in a flat place where there’s practically no life. The small family unit formed by mother and son hardly ever receives visitors, and their goal is to lead a quiet existence. At first they succeed, but the appearance of a mysterious, violent creature that starts stalking their small house will put the relationship that unites them to the test.
Abraham and his female friend Álex have a close relationship; they share both secrets and fears. When Abraham starts going out with Anchi, he begins to distance himself from Álex, who gradually dives into a living hell where she encounters strange apparitions, nightmarish visions and extreme situations.
Two investigators of paranormal hoaxes, the veteran Dr. Margaret Matheson and her young assistant, Tom Buckley, study the most varied metaphysical phenomena with the aim of proving their fraudulent origins. Simon Silver, a legendary blind psychic, reappears after an enigmatic absence of 30 years to become the greatest international challenge to both orthodox science and professional sceptics. Tom starts to develop an intense obsession with Silver, whose magnetism becomes stronger with each new manifestation of inexplicable events. As Tom gets closer to Silver, tension mounts, and his worldview is threatened to its core.
Ángela Vidal the young television reporter who entered the building with the fireman, manages to make it out alive. But what the soldiers don?t know is that she carries the seed of the strange infection. She is to be taken to a provisional quarantine facility, a high-security installation where she will have to stay in isolation for several days. An old oil tanker, miles off shore and surrounded by water on all sides, has been especially equipped for the quarantine.
Kit, a troubled girl, is sent to the exclusive Blackwood boarding school, where she discovers that only four other female students have been admitted to learn the four pillars of knowledge under the ominous wing of the mysterious headmistress Madame Duret.
The action now takes place miles away from the original location and partly in broad daylight, giving the film an entirely fresh yet disturbing new reality. The infection has left the building. In a clever twist that draws together the plots of the first two movies, this third part of the saga also works as a decoder to uncover information hidden in the first two films and leaves the door open for the final installment, the future 'REC 4 Apocalypse.'
