Columbus (Jesse Eisenberg) has made a habit of running from what scares him. Tallahassee (Woody Harrelson) doesnt have fears. If he did, hed kick their ever-living ass. In a world overrun by zombies, these two are perfectly evolved survivors. But now, theyre about to stare down the most terrifying prospect of all: each other.
When a depressed woman is burglarized, she finds a new sense of purpose by tracking down the thieves alongside her obnoxious neighbor. But they soon find themselves dangerously out of their depth against a pack of degenerate criminals.