A group of renegade marine commandos seizes a stockpile of chemical weapons and takes over Alcatraz, with 81 tourists as hostages. Their leader demands $100 million to be paid, as restitution to families of Marines who died in covert ops. Otherwise, he will launch 15 rockets carrying deadly VX gas into the San Francisco Bay area.
Martin Lawrence and Will Smith reunite as out-of-control trash-talking buddy cops Marcus Burnett and Mike Lowrey of the Miami Narcotics Task Force. Bullets fly, cars crash, and laughs explode as they pursue a whacked-out drug lord from the streets of Miami to the barrios of Cuba. But the real fireworks result when Lawrence discovers that playboy Smith is secretly romancing his sexy sister Syd.
Marcus Burnett is a hen-pecked family man. Mike Lowry is a foot-loose and fancy free ladies' man. Both are Miami policemen, and both have 72 hours to reclaim a consignment of drugs stolen from under their station's nose. To complicate matters, in order to get the assistance of the sole witness to a murder, they have to pretend to be each other.
After making their way through high school (twice), big changes are in store for officers Schmidt and Jenko when they go deep undercover at a local college. But when Jenko meets a kindred spirit on the football team, and Schmidt infiltrates the bohemian art major scene, they begin to question their partnership. Now they don't have to just crack the case - they have to figure out if they can have a mature relationship. If these two overgrown adolescents can grow from freshmen into real men, college might be the best thing that ever happened to them.
When a Las Vegas performer-turned-snitch named Buddy Israel decides to turn state's evidence and testify against the mob, it seems that a whole lot of people would like to make sure he's no longer breathing.